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Table 1 Characteristics of the studies with lesion response and lesion size changes after PDT

From: Efficacy evaluation of photodynamic therapy for oral lichen planus: a systematic review and meta-analysis

Author Year Light sources Photosensitizer Lesion types Administration Method Lesion locations Sample size CR PR lesion size of pre-PDT lesion size of post-PDT
Mean SD Mean SD
Aghahosseini F 2006 diode laser MB mixed gargle mixed 26 4 12 1.8 0.7 1 0.9
Sadaksharam J 2012 xenon lamp MB mixed gargle mixed 20 0 10     
Sobaniec S 2013 semiconductor laser chlorin e6 derivative mixed topical mixed 48 14 25 6 4.5 2.7 2.62
       BM/L 40 13 22 6.6 4.63 2.8 2.81
       T/G 8 1 3 3 1.9 2.1 1.21
Prasanna SW 2015 metal halide lamp MB mixed gargle mixed 15 0 13 3 1.6 0.8 1
Maloth KN 2016 LED 5-ALA mixed topical mixed 10 0 8 2.22 0.79 1.41 0.74
Bakhtiari S 2017 LED MB mixed gargle mixed 15 0 2     
Mostafa D 2017 diode laser MB mixed gargle mixed 19 7 9     
Sulewska M 2017 LED 5-ALA erosive topical mixed 22 5 11 1.49 1.45 1.37 1.78
  BM 16 4 7 1.06 0.98 1.08 1.57
  T /G 6 1 4 2.63 1.93 2.13 2.24
Rakesh N 2018 diode laser 5-ALA erosive topical mixed 10 0 10     
Sulewska M 2019 LED 5-ALA reticular topical mixed 124 46 63 3.99 3.73 1.48 1.98
  BM 80 27 44 4.58 4.01 1.67 2.04
  T /G 44 19 19 2.93 2.91 1.13 1.84
  1. PDT Photodynamic therapy, GaAlAs Gallium-Aluminum-Arsenide, LED Light emitting diode, TB Toluidine blue, 5-ALA 5 aminolevulinic acid, MB Methylene Blue, BM/L Buccal mucosa and/or lips, T/G Tongue and/or gingival mucosa; mixed: with different required information or information were not mentioned, CR Complete response, PR Partial response, NR No response, SD Standard deviation